Year : 2020 | Volume
: 9 | Issue : 1 | Page : 45-
Predictors of long-term mortality after first-ever stroke
Hossein Novbakht1, Seyed Morteza Shamshirgaran2, Parvin Sarbakhsh1, Darioush Savadi-Oskouei3, Mohammad Marandi Yazdchi3, Zohreh Ghorbani1
1 Department of Statistics and Epidemiology, Faculty of Health Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
2 Healthy Aging Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran
3 Neurosciences Research Centre, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
BACKGROUND AND OBJECTIVE: Data on the factors affecting long-term mortality following a stroke in Iran are scarce. The current research aimed at investigating the extent of 2-year mortality following a stroke and the factors affecting it in the northwest of Iran.
MATERIALS AND METHODS: This prospective cohort study was conducted in Tabriz, Northwest of Iran. Patients with computed tomography/magnetic resonance imaging confirmed the first-ever stroke were included in this study and followed up to 2 years. Clinical examinations, including the severity of the stroke using the modified National Institutes of Health Stroke Scale (mNIHSS), were conducted by a neurologist. The general characteristics, lifestyle factors, and laboratory tests were also completed. To estimate the survival, Kaplan–Meier analysis was used; and for group comparison, the log-rank method was applied. To identify the factors predicting 2-year mortality, semiparametric Cox regression analysis was used.
RESULTS: A total of 1036 first-ever stroke patients were included in the present study. The mortality rates of stroke in 6-month, 1-year, and 2-years follow-up periods were 31.6%, 34.5%, and 38%, respectively. The two-year mortality rate was 33.6% in ischemic and 58.7% in hemorrhagic stroke (P < 0.001). In the multivariate Cox model, variables age, type of stroke, diabetes, and severity of the stroke, according to the mNIHSS index, were identified as factors predicting 2-year mortality following the stroke.
CONCLUSION: The 2-year mortality following acute stroke was relatively high compared to that of in developed countries. Implementation of secondary prevention is recommended to better management of modifiable predictors of mortality.
Dr. Seyed Morteza Shamshirgaran
Healthy Aging Research Centre, Neyshabur University of Medical Sciences, Janbazan Blvd, Razavi Khorasan, Neyshabur
|How to cite this article:|
Novbakht H, Shamshirgaran SM, Sarbakhsh P, Savadi-Oskouei D, Yazdchi MM, Ghorbani Z. Predictors of long-term mortality after first-ever stroke.J Edu Health Promot 2020;9:45-45
|How to cite this URL:|
Novbakht H, Shamshirgaran SM, Sarbakhsh P, Savadi-Oskouei D, Yazdchi MM, Ghorbani Z. Predictors of long-term mortality after first-ever stroke. J Edu Health Promot [serial online] 2020 [cited 2020 May 27 ];9:45-45
Available from: http://www.jehp.net/article.asp?issn=2277-9531;year=2020;volume=9;issue=1;spage=45;epage=45;aulast=Novbakht;type=0